FOR IMMEDIATE RELEASE September 22, 2004 For more information: Scott Place Maverick Marketing Office: 919.459.2772 Cell: 919.271.5788 splace@maverickmarketing.com

iAdvantage Software and OnSphere Corporation Announce Strategic Alliance The companies will collaborate to provide complete data and document management solutions to the pharmaceutical industry

CARY, NC (September 22, 2004)  —  iAdvantage Software, Inc., a leading provider of web-based data management solutions for drug development companies, and OnSphere Corporation, a web-based business application development and integration company, today announced a formal strategic alliance to offer bundled, web-based, compliant data and document management solutions to the pharmaceutical industry. "iAdvantage's partnership with OnSphere will help solve our clients' need for compliant, affordable document management," said Fate Thompson, Ph.D., president and CEO of iAdvantage Software. "The combination of OnSphere's PharmaReady™ for document management and iAdvantage's study data management and reporting tools provides a seamless electronic drug development workflow process. I have complete confidence that this alliance will provide a successful solution for our clients, further streamlining the research and development process and improving speed to market." iAdvantage Software's flagship suite, the Biotech Management System™, is a comprehensive, web-based data management system that allows scientists to collect, manage and report research data in a flexible and efficient manner. The system includes Web Data Collector™, which gives users complete control over data collection forms, and Document Generator™, a program that allows users to define the content and format of reports. OnSphere's PharmaReady solution provides a regulatory-compliant, cost-effective document management system that is easy to implement, install and maintain. Using proven technology from Microsoft ®, the web-based application allows quick and reliable access to documentation from anywhere in the world. "We are extremely pleased to form this strategic relationship with iAdvantage," said Phillip Mosely, president of OnSphere. "Our alliance will further provide our current and future clients with a better solution to manage their study data, reports and documents. With OnSphere's PharmaReady and the iAdvantage Document Generator, life science organizations are now able to go to a single solution for study data management and documentation where both Part 11 compliance and affordability are important business drivers." About iAdvantage Software, Inc. iAdvantage Software provides web-based data management solutions for life science research and development, enabling scientists to increase their productivity in study design, data collection and data reporting. Scientists save time and money while maintaining data integrity (complying with 21 CFR Part 11 regulations) by using the company's Biotech Management System™, Web Data Collector™ and Document Generator™ products. iAdvantage is headquartered in Cary, North Carolina, near the life science and biotech hub of Research Triangle Park. More than 140 companies in North America and Europe, including multinational life science companies, successfully use the company's products in their life science research and development. For more information, please visit www.iadvantagesoftware.com. About OnSphere Corporation OnSphere is a proven leader in Microsoft-based regulatory compliant software solutions and validation services. In 2003, OnSphere launched its FDA-compliant document management system utilizing Microsoft SharePoint and .NET technologies. PharmaReady™ is designed specifically for pharmaceutical, biotech and contract research organizations requiring document management in FDA-validated environments. OnSphere was founded in 1988 and is headquartered in Raleigh, North Carolina. Learn more about OnSphere at www.onsphere.com. ###